Given the lack of a research-based classification and in recognition of the physiological changes that distinguish an adrenal crisis from a milder episode of hypoadrenalism, 5-11 pragmatic definitions of adrenal crisis have generally been adopted. 2,5,6 Diagnostic misclassification may not alter immediate management but, at the epidemiologic level, can impede an understanding of the nature of adrenal crises. 5 Generally, acute physiological disturbances in patients with known hypoadrenalism are labeled as adrenal crises on the basis of clinical assessment. There is no universally accepted definition of an adrenal crisis, also called acute adrenal insufficiency or addisonian crisis. The most trusted, influential source of new medical knowledge and clinical best practices in the world. Information and tools for librarians about site license offerings.

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Definition of adrenal